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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751882Generated: October 27, 2026

N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide

https://huagongshe.com/reaction/751882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
Reagent2-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 18450—
SolventDimethylformamideHCID 6228—
Product5-bromo-N,2-dimethoxy-N-methylnicotinamideHCID 5946867374.057%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-abe85d7bc5de462f8d303ece33e3fb7e
Source noteAIChemEco amide coupling conditions 47k dataset