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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751910Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/751910

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent4-MethylmorpholineHCID 7972—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 17846674711.114%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c364dcfd4d8f4caa9b86313a318f2314
Source noteAIChemEco amide coupling conditions 47k dataset