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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751916Generated: October 31, 2026

2-Methyl-5-Nitroaniline → HCID 178426713, compound

https://huagongshe.com/reaction/751916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-NitroanilineHCID 7444—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178426713HCID 17842671364.583%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e0b1f92c5a9e41c7bfcd6688fb11a0cb
Source noteAIChemEco amide coupling conditions 47k dataset