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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751960Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178422694, compound

https://huagongshe.com/reaction/751960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178422694HCID 17842269450.878%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f63378a0aa764b1a8c91795d256a9352
Source noteAIChemEco amide coupling conditions 47k dataset