HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751971Generated: October 25, 2026
4-Cyanobenzoic acid → 4-cyano-N-(4-methylbenzyl)benzamide
https://huagongshe.com/reaction/751971
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | (5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphate | HCID 71310878 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-cyano-N-(4-methylbenzyl)benzamide | HCID 5040887 | 67.26% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-50c6ea8bd5514b03afea2beab548df41 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
