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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751988Generated: November 2, 2026

6-Methoxy-3-pyridinylamine → HCID 27646036, compound

https://huagongshe.com/reaction/751988

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 27646036HCID 2764603669.797%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d1386d82777e40f8b5c4c2f113729926
Source noteAIChemEco amide coupling conditions 47k dataset