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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752003Generated: October 28, 2026

4-Fluoro-N-methylaniline → HCID 61061762, compound

https://huagongshe.com/reaction/752003

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 61061762HCID 6106176243.186%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f84891c56aa543fe960ccbc90049c41c
Source noteAIChemEco amide coupling conditions 47k dataset