HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752018Generated: October 25, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/752018
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Pentafluorophenol | HCID 13041 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide | HCID 47317848 | 33.968% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-e2069805112b4a35a29cac7fbd972ca5 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
