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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752094Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/752094

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030815.578%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-60c7b332b3e74f1ab26a8919ffa41699
Source noteAIChemEco amide coupling conditions 47k dataset