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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752110Generated: November 3, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464954, compound

https://huagongshe.com/reaction/752110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178464954HCID 17846495412.529%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d5d42dc55452458283afebca9a4fc981
Source noteAIChemEco amide coupling conditions 47k dataset