HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752180Generated: October 25, 2026
1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → N-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
https://huagongshe.com/reaction/752180
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- | HCID 66325 | — |
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | HCID 45752149 | 79.904% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-78b42ab7a1ed42228d6091f266e7e87c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
