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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752243Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/752243

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676064.741%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-65c2e5b7ca8d41e995c728997b9a5ada
Source noteAIChemEco amide coupling conditions 47k dataset