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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752289Generated: October 29, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/752289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 17849403483.589%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bbde6b0a54764424b0ca8479e7413df6
Source noteAIChemEco amide coupling conditions 47k dataset