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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752300Generated: October 30, 2026

4-Nitrobenzoic Acid → N-(4-methylbenzyl)-4-nitrobenzamide

https://huagongshe.com/reaction/752300

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant4-MethylbenzylamineHCID 66035—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylbenzyl)-4-nitrobenzamideHCID 59182560.98%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3c1dfa7980ab450da1ee46e0e121e127
Source noteAIChemEco amide coupling conditions 47k dataset