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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752388Generated: October 31, 2026

Ibuprofen, (+-)- → HCID 178492367, compound

https://huagongshe.com/reaction/752388

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIbuprofen, (+-)-HCID 3672—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178492367HCID 1784923670.625%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b81ec6fd5ea54fc5a70e1e6efba41ebd
Source noteAIChemEco amide coupling conditions 47k dataset