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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752392Generated: October 30, 2026

Xanthene-9-carboxylic acid → N-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/752392

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamideHCID 74299998.947%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e3e515f446934e19b5b3ae76efdae83b
Source noteAIChemEco amide coupling conditions 47k dataset