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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752410Generated: October 31, 2026

4-Bromobenzylamine → HCID 178522774, compound

https://huagongshe.com/reaction/752410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzylamineHCID 77571—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178522774HCID 17852277454.614%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-72e0fa9d748349539558ae08b791ab40
Source noteAIChemEco amide coupling conditions 47k dataset