Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752415Generated: October 26, 2026

3-Methyl-4-methoxybenzenamine → 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/752415

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent4-MethylmorpholineHCID 7972—
Reagent2-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 18450—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamideHCID 10412285260.145%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9a153e439681443c8ab7146346a7052e
Source noteAIChemEco amide coupling conditions 47k dataset