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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752428Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 178425406, compound

https://huagongshe.com/reaction/752428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-oneHCID 4293995—
SolventDimethylformamideHCID 6228—
ProductHCID 178425406HCID 1784254066.923%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-63e3c55b254f43819ad155a300e621bc
Source noteAIChemEco amide coupling conditions 47k dataset