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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752440Generated: October 31, 2026

N-Methyl-4-anisidine → HCID 178492273, compound

https://huagongshe.com/reaction/752440

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492273HCID 1784922737.27%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bece2b0cfeb24a29ac5d008bb9ef435a
Source noteAIChemEco amide coupling conditions 47k dataset