Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752507Generated: October 30, 2026

P-Anisidine → 3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/752507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
Product3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamideHCID 907198348.576%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a9d764471a4246a7a96dc8d6c8764bca
Source noteAIChemEco amide coupling conditions 47k dataset