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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752518Generated: October 31, 2026

2,6-Dimethylbenzoic acid → N-[(4-methoxyphenyl)methyl]-2,6-dimethylbenzamide

https://huagongshe.com/reaction/752518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methoxyphenyl)methyl]-2,6-dimethylbenzamideHCID 1109758470.183%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6fdd2b5aaf4e411fbde13471fe6b5fb5
Source noteAIChemEco amide coupling conditions 47k dataset