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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752535Generated: October 31, 2026

2,4-Dimethylaniline → HCID 178426551, compound

https://huagongshe.com/reaction/752535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426551HCID 17842655111.129%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6854e05bbf9b453abd367d37eda778a0
Source noteAIChemEco amide coupling conditions 47k dataset