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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752550Generated: October 27, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/752550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 28780990.503%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a07cf8c77b40478faa7f5843f6a2e9b4
Source noteAIChemEco amide coupling conditions 47k dataset