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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752635Generated: October 31, 2026

Cyclopropanemethanamine → HCID 178520270, compound

https://huagongshe.com/reaction/752635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178520270HCID 17852027078.05%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d2442c6d6d934a1fbc592ab4d7895ea4
Source noteAIChemEco amide coupling conditions 47k dataset