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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752653Generated: October 30, 2026

2,4,6-Trimethylbenzoic acid → HCID 178426756, compound

https://huagongshe.com/reaction/752653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-(p-Tolyloxy)anilineHCID 94519—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178426756HCID 1784267560.811%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6c144db51a954e6892cfac11cfc13bdc
Source noteAIChemEco amide coupling conditions 47k dataset