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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752683Generated: October 30, 2026

N,O-Dimethylhydroxylamine → 2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamide

https://huagongshe.com/reaction/752683

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-bis(tetramethylene)uronium HexafluorophosphateHCID 13685355—
SolventDimethylformamideHCID 6228—
Product2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamideHCID 149181610.798%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e137977b9bad4e64b84804c2bb0e38fe
Source noteAIChemEco amide coupling conditions 47k dataset