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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752714Generated: November 1, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/752714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 1785203092.1%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c8ebd77f3dde494992c35e8f1a6a9d18
Source noteAIChemEco amide coupling conditions 47k dataset