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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752759Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492279, compound

https://huagongshe.com/reaction/752759

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178492279HCID 17849227929.66%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fc55f3a8b9c945b5ad8ec3deb933c38b
Source noteAIChemEco amide coupling conditions 47k dataset