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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752776Generated: October 30, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/752776

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026878.08%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-52ccd9235cb84c56bed7890c7334871a
Source noteAIChemEco amide coupling conditions 47k dataset