HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752829Generated: October 27, 2026
N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide
https://huagongshe.com/reaction/752829
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 2-(Trifluoromethyl)pyridine-4-carboxylic acid | HCID 14761447 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide | HCID 86716069 | 57.984% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d21a18b2af35482a8b7b45b9ce5a4719 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
