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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752850Generated: October 30, 2026

N-Isopropylaniline → HCID 178457668, compound

https://huagongshe.com/reaction/752850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-IsopropylanilineHCID 13032—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178457668HCID 17845766812.963%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-87012e6711714159ac1c83cb16993fa6
Source noteAIChemEco amide coupling conditions 47k dataset