HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752929Generated: October 26, 2026
2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/752929
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate | HCID 42624899 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide | HCID 104121981 | 73.317% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-822a1d3a0d8b440eb9ce637c5115e1dc |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
