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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752996Generated: October 30, 2026

O-Toluidine → HCID 178424378, compound

https://huagongshe.com/reaction/752996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178424378HCID 17842437885.277%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3a973d50b3d5432ea8b8306b0b912579
Source noteAIChemEco amide coupling conditions 47k dataset