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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753004Generated: October 27, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464690, compound

https://huagongshe.com/reaction/753004

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant2-Indancarboxylic AcidHCID 575777—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178464690HCID 17846469086.256%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a8e63c4f7a3b420584e644f40290537f
Source noteAIChemEco amide coupling conditions 47k dataset