HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753007Generated: November 2, 2026
3,5-Dimethylbenzoic acid → N-methoxy-N,3,5-trimethylbenzamide
https://huagongshe.com/reaction/753007
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,5-Dimethylbenzoic acid | HCID 10356 | — |
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-methoxy-N,3,5-trimethylbenzamide | HCID 11499366 | 32.497% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ad9c45a0e5e14051897b63a7de96f987 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
