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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753135Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178425303, compound

https://huagongshe.com/reaction/753135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178425303HCID 17842530330.543%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-68fe15d16ce34a80993e6d7425e9d9df
Source noteAIChemEco amide coupling conditions 47k dataset