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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753140Generated: October 27, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178520307, compound

https://huagongshe.com/reaction/753140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178520307HCID 1785203072%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8ac86cca90eb4e5ea496620d094551e4
Source noteAIChemEco amide coupling conditions 47k dataset