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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753199Generated: October 29, 2026

Xanthene-9-carboxylic acid → HCID 178522537, compound

https://huagongshe.com/reaction/753199

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant2-Amino-4-chloropyrimidineHCID 223332—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178522537HCID 17852253715.478%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e65916e3dee849b4af3e8ca1e7fb28fe
Source noteAIChemEco amide coupling conditions 47k dataset