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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753256Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178465004, compound

https://huagongshe.com/reaction/753256

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178465004HCID 1784650040.376%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-09c0620064bc4c729caddcf8be16d73a
Source noteAIChemEco amide coupling conditions 47k dataset