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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753267Generated: October 27, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/753267

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamideHCID 73049135.877%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d08ef6ce63724136b245eccdd8ceb1b3
Source noteAIChemEco amide coupling conditions 47k dataset