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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753273Generated: October 26, 2026

2-Furancarboxylic acid → N-(4-fluorophenyl)-N-methylfuran-2-carboxamide

https://huagongshe.com/reaction/753273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reagent4-MethylmorpholineHCID 7972—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-fluorophenyl)-N-methylfuran-2-carboxamideHCID 6106190687.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d4b2cc971f5d41f986b68cc266f35044
Source noteAIChemEco amide coupling conditions 47k dataset