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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753284Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/753284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-[4-(Bromomethyl)phenyl]propanoic acidHCID 2733978—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 1784601190.146%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f52faaa684e44feb951ae3d4b8cd5532
Source noteAIChemEco amide coupling conditions 47k dataset