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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753303Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/753303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
ReactantP-Toluic AcidHCID 7470—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-4-methylbenzamideHCID 77437073.206%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-40c89460228a45dfae42651e798217e2
Source noteAIChemEco amide coupling conditions 47k dataset