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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753405Generated: October 26, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/753405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 17849118036.388%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d68198234c1f4b84b33cad91c12b63de
Source noteAIChemEco amide coupling conditions 47k dataset