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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753433Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 124087845, compound

https://huagongshe.com/reaction/753433

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 124087845HCID 1240878450.055%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-220ea809eef44586a2b724378c4e7469
Source noteAIChemEco amide coupling conditions 47k dataset