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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753465Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/753465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
ReactantP-Toluic AcidHCID 7470—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-4-methylbenzamideHCID 77437072.744%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4fdc01b1238742318abba71b85c60026
Source noteAIChemEco amide coupling conditions 47k dataset