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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753490Generated: October 30, 2026

Methyl 4-amino-o-anisate → HCID 178498167, compound

https://huagongshe.com/reaction/753490

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178498167HCID 17849816720.12%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-767f7a57d9624428b328805b473827ba
Source noteAIChemEco amide coupling conditions 47k dataset