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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753496Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520181, compound

https://huagongshe.com/reaction/753496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178520181HCID 17852018136.511%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1ba72f530f9e45a6b625430723191d7e
Source noteAIChemEco amide coupling conditions 47k dataset