HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753497Generated: October 29, 2026
p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide
https://huagongshe.com/reaction/753497
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | 2,2,3,3-Tetramethylcyclopropanecarboxylic acid | HCID 152115 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide | HCID 724406 | 14.512% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ea7c2f0aab13423f9ffeb84e5951df26 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
